Which of the following is a hereditary disorder that causes degeneration of GABA- secreting neurons in the putamen of the basal ganglia?
A) Huntington's disease
B) Tay-Sachs disease
C) Meissner's syndrome
D) Down syndrome
E) Parkinson's disease

Question

Quizplus · Accepted Answer

Huntington's disease is a hereditary disorder that causes degeneration of GABA-secreting neurons in the putamen of the basal ganglia, leading to symptoms such as chorea, dementia, and psychiatric disturbances. Tay-Sachs disease is a lysosomal storage disorder that affects the breakdown of certain fats and is not associated with the basal ganglia. Meissner's syndrome and Down syndrome are also not associated with the basal ganglia. While Parkinson's disease is also a degenerative disorder of the basal ganglia, it primarily affects dopaminergic neurons in the substantia nigra rather than GABA-secreting neurons in the putamen.

Which of the Following Is a Hereditary Disorder That Causes