Which of the following is a research finding that is inconsistent with the monoamine hypothesis of depression?
A) Drugs that increase serotonergic activity are effective in treating depression.
B) Increases in noradrenergic activity have been seen in the brains of depressed patients.
C) Heightened sensitivity to drugs that increase GABA activity is commonly seen in individuals with bipolar disorder.
D) Tricyclic antidepressants work by blocking monoamine reuptake.

Question

Quizplus · Accepted Answer

The monoamine hypothesis of depression suggests that depression is caused by a deficiency in monoamine neurotransmitters such as serotonin, norepinephrine, and dopamine. However, research has found that increases in noradrenergic (norepinephrine) activity have been seen in the brains of depressed patients, which contradicts the hypothesis. The other options are consistent with the monoamine hypothesis.

Which of the Following Is a Research Finding That Is