Two individuals administered the same dose of a psychotropic drug for the very first time may exhibit very different reactions to the drug.This is most likely due to
A)context-specific tolerance
B)pharmacodynamic tolerance
C)dispositional or genetic tolerance
D)conventional tolerance

Question

Quizplus · Accepted Answer

Dispositional or genetic tolerance refers to differences in an individual's metabolism and ability to respond to a drug based on their unique genetic makeup and physiological characteristics. This can result in different reactions to the same dose of a drug, as well as variations in how the drug is metabolized and eliminated from the body. Context-specific tolerance (A) refers to an individual's tolerance to a drug being influenced by the environment in which it is taken, pharmacodynamic tolerance (B) refers to changes in the body's response to a drug over time due to repeated exposure, and conventional tolerance (D) refers to a decrease in a drug's effectiveness over time. While some of these factors may contribute to individual differences in drug response, dispositional or genetic tolerance is likely the primary cause of variability in drug reactions between individuals.

Two Individuals Administered the Same Dose of a Psychotropic Drug