A mutation causes the sliding DNA clamp to operate less efficiently.What is the most likely consequence of this mutation?
A) The leading strand becomes the lagging strand.
B) Okazaki fragments are not joined together.
C) Okazaki fragments are produced.
D) The helicase does not function efficiently.
E) DNA replication proceeds more slowly.

Question

Quizplus · Accepted Answer

The sliding DNA clamp plays an important role in DNA replication by keeping the DNA polymerase attached to the template strand. If the clamp operates less efficiently due to a mutation, it is likely that the DNA polymerase will dissociate from the strand more frequently, slowing down replication.

A Mutation Causes the Sliding DNA Clamp to Operate Less