A mutation frequently causes a chromosome of a cell line to become detached from the spindle.The most likely consequence of this mutation is that _______ cells will be stopped at the _______ checkpoint.
A) more; G1
B) more; G2
C) fewer; G1
D) more; M
E) fewer; M

Question

Quizplus · Accepted Answer

The spindle assembly checkpoint occurs during metaphase of mitosis (M phase) to ensure that all chromosomes are properly attached to the spindle before anaphase proceeds. A mutation causing chromosomes to detach from the spindle would likely cause more cells to be stopped at this checkpoint to prevent progression until the issue is resolved.

A Mutation Frequently Causes a Chromosome of a Cell Line