Replacing arginine in a histone with a neutral amino acid would make the histone _______ positively charged and _______ likely to bind to DNA.
A) more; more
B) more; less
C) less; more
D) less; less
E) None of the above; this replacement would have no effect because arginine is a neutral amino acid.

Question

Quizplus · Accepted Answer

Arginine is a positively charged amino acid. Replacing it with a neutral amino acid would make the histone less positively charged, reducing its affinity for the negatively charged DNA, thus making it less likely to bind to DNA.

Replacing Arginine in a Histone with a Neutral Amino Acid