Scientists Have Researched Methods to Transplant Stem Cells to Human

Scientists have researched methods to transplant stem cells to human heart tissue to repair severe damage by cardiovascular disease.Studies in model systems have shown that if the transplanted stem cells are not washed with a buffered saline solution before transplantation, they adhere, adapt, and survive better.Which statement best explains this observation?

A) The microenvironment surrounding stem cells is improved by a washing step before transplantation.
B) A supportive environment for stem cell adhesion to existing heart tissue is supplied by the extracellular matrix surrounding the stem cells.
C) Transplanted stem cells require certain proteins and proteoglycans present in the extracellular matrix of the damaged heart tissue.
D) The extracellular matrix surrounding the damaged heart tissue provides all the necessary proteins and proteoglycans for adherence of transplanted cells.
E) Biomolecules necessary for successful transplantation are secreted into the stem cells' extracellular matrix when the cells are stimulated by a washing step before transplantation.