Metabolically active tissues have which of the following sets of conditions that shift the oxyhemoglobin dissociation curve to the right? A) ↑ PO₂,↓ PCO₂,↑ temperature,↑ BPG B) ↓ PO₂,↑ PCO₂,↑ temperature,↑ BPG C) ↓ PO₂,↑ PCO₂,↓ temperature,↑ BPG D) ↑ PO₂,↓ PCO₂,↑ temperature,↓ BPG

Question

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Metabolically active tissues have high levels of carbon dioxide (PCO2) and low levels of pH and oxygen (PO2), which shift the oxyhemoglobin dissociation curve to the right. Additionally, an increase in temperature and the concentration of 2,3-bisphosphoglycerate (BPG) also shift the curve to the right. Choice B correctly reflects an increase in PCO2, decrease in pH, increase in temperature, and increase in BPG, all of which shift the curve to the right.

Metabolically Active Tissues Have Which of the Following Sets of Conditions