Which of the following laboratory methods will give the most detailed information regarding whether TP53 mutations are present in a patient's tumor cells?

Question

Quizplus · Accepted Answer

Direct sequencing is considered the gold standard method for detecting mutations in genes. It involves amplifying and then sequencing the region of interest, providing highly detailed information on the presence and type of mutations in the TP53 gene. Pulsed field gel electrophoresis, polymerase chain reaction, and Southern blotting are not designed for detecting mutations in specific genes and therefore may not provide as detailed information on TP53 mutations.

Which of the Following Laboratory Methods Will Give the Most