According to the Focus on Neuroscience box: The Addicted Brain, what is the biological basis for drug tolerance?
A)The brain's reward pathways adapt to the high dopamine levels, with repeated drug use.
B)Addictive drugs gradually create new but abnormal neural pathways in the brain's limbic system.
C)As the brain adjusts to the addictive substance, the threshold to activate neurons in the brain's motor and sensory areas is greatly increased.
D)The brain counteracts the effects of the addictive drug by overproducing the neurotransmitter serotonin.

Question

Quizplus · Accepted Answer

Drug tolerance occurs when the brain's reward pathways adapt to the high levels of dopamine caused by repeated drug use. The brain becomes less responsive to the drug over time, and individuals need higher doses to achieve the same effect.

According to the Focus on Neuroscience Box: the Addicted Brain