All of the following are true of the classical pathway of complement activation except one.Select the one answer that does not describe the classical pathway of complement activation.
A) It is an example of overlap between innate and adaptive immune function.
B) Classical activation will result in enhanced inflammation, opsonization as well as formation of MAC proteins.
C) It requires that circulating antibodies are bound to antigens.
D) It activates T-helper cells by presenting antigen to them.

Question

Quizplus · Accepted Answer

The classical pathway of complement activation does not activate T-helper cells by presenting antigen to them. This is a function of the adaptive immune system, whereas the classical pathway is an example of overlap between innate and adaptive immune function. The other options are true of the classical pathway - it requires the binding of antibodies to antigens, results in enhanced inflammation, opsonization, and formation of MAC proteins.

All of the Following Are True of the Classical Pathway