When the 1,7-diester CH₃O₂CCH₂CH₂CH(CH₃)CH₂CH₂CO₂CH₃ is treated with sodium methoxide and the reaction mixture is subsequently neutralized with acid,what kind of compound is the major organic product? A)an acyclic β-diketone B)an acyclic β-ketoacid C)an acyclic β-diester D)a cyclic β-ketoester E)a cyclic β-diketone

Question

Quizplus · Accepted Answer

The treatment with sodium methoxide followed by acid neutralization leads to an intramolecular Claisen condensation, forming a cyclic β-ketoester as the major product.

When the 1,7-Diester CH3O2CCH2CH2CH(CH3)CH2CH2CO2CH3 Is Treated with Sodium Methoxide and the Reaction

When the 1,7-Diester CH₃O₂CCH₂CH₂CH(CH₃)CH₂CH₂CO₂CH₃ Is Treated with Sodium Methoxide and the Reaction