Evidence suggests that the induction of LTP is postsynaptic and the maintenance and expression involve presynaptic changes. This implies the existence of a retrograde messenger. Recent studies suggest that this messenger may be
A) glutamate.
B) dopamine.
C) serotonin.
D) nitric oxide.
E) NMDA.

Question

Quizplus · Accepted Answer

Nitric oxide is a retrograde messenger involved in the maintenance and expression of LTP. Studies have shown that inhibition of nitric oxide synthesis impairs LTP, while the application of nitric oxide donors enhances LTP.

Evidence Suggests That the Induction of LTP Is Postsynaptic and the Maintenance