Frameshift mutations may involve
A) substitution of nucleotides.
B) substitution of codons.
C) substitution of amino acids.
D) insertion of one to several base pairs.
E) all of these.

Question

Quizplus · Accepted Answer

Frameshift mutations involve the insertion or deletion of one or more nucleotides, which alters the reading frame of the codons in the gene. This can result in a completely different amino acid sequence, which can have severe effects on the resulting protein. Substitution mutations, on the other hand, usually only affect a single codon and may or may not result in a change in the amino acid sequence. Therefore, the correct answer is D, which involves the insertion of one to several base pairs.

Frameshift Mutations May Involve