Selection against a deleterious recessive allele is replenished in the population by mutation,and leads to a dynamic equilibrium in which the frequency of the recessive allele is a simple function of the mutation rate and the selection coefficient.Which formula represents this situation?
A) p²+2pq+q²
D) 1/2N
E) None of these

Question

Selection against a deleterious recessive allele is replenished in the population by mutation,and leads to a dynamic equilibrium in which the frequency of the recessive allele is a simple function of the mutation rate and the selection coefficient.Which formula represents this situation?
A) p²+2pq+q² 
D) 1/2N 
E) None of these

Quizplus · Accepted Answer

The formula that represents this situation is the Hardy-Weinberg equilibrium equation, which is p² + 2pq + q² = 1. In this case, the frequency of the deleterious recessive allele is represented by q, and the selection coefficient is represented by s. The equilibrium frequency of the recessive allele can be calculated using the formula q = √(μ/s), where μ is the mutation rate. Therefore, the frequency of the recessive allele will be a simple function of the mutation rate and the selection coefficient. Choice C is the only option that represents a modified version of the Hardy-Weinberg equation, which fits this situation.

Selection Against a Deleterious Recessive Allele Is Replenished in the Population