DNA regions which are locally unwound because transcription has begun,and which are sensitive to low doses of DNAse 1 are known as
A) RNase hypersensitive sites.
B) RNase hyposensitive sites.
C) DNase 1 hypersensitive sites.
D) DNase 1 hyposensitive sites.
E) None of these are correct.

Question

Quizplus · Accepted Answer

DNase 1 hypersensitive sites are regions of DNA that are sensitive to the enzyme DNase 1, which cleaves DNA at locations where the DNA is not tightly packaged. These hypersensitive sites occur where the DNA is locally unwound due to transcription initiation or other factors, and can be used to identify regulatory elements such as promoters and enhancers. RNase hypersensitive sites do not exist, and RNase hyposensitive sites are not sensitive to the RNase enzyme. DNase 1 hyposensitive sites do exist but are not relevant to this question.

DNA Regions Which Are Locally Unwound Because Transcription Has Begun,and