Inflammation begins when _______________ release the contents of their granules into an affected tissue.
A) eosinophils and neutrophils
B) dendritic cells and basophils
C) macrophages and neutrophils
D) basophils, neutrophils, and mast cells
E) B cells, leukocytes, and basophils

Question

Inflammation begins when _______________ release the contents of their granules into an affected tissue.  
A) eosinophils and neutrophils
B) dendritic cells and basophils
C) macrophages and neutrophils
D) basophils, neutrophils, and mast cells
E) B cells, leukocytes, and basophils

Quizplus · Accepted Answer

Mast cells are the cells that release the contents of their granules, containing histamine and other inflammatory mediators, in response to tissue injury or infection. Neutrophils and basophils are also capable of releasing granules, but mast cells are the primary initiators of inflammation through this process. Therefore, option D, which includes all three cell types, is the best choice.

Inflammation Begins When _______________ Release the Contents of Their Granules