The membrane attack stage of the complement cascade involves
A)initiation of the cascade.
B)production of inflammatory cytokines.
C)a ring-shaped protein digests holes in bacterial cell membranes and virus envelopes.
D)cleaving of C3 to yield C3a and C3b.
E)C1q binds to surface receptors on a membrane.

Question

Quizplus · Accepted Answer

The membrane attack stage of the complement cascade involves the formation of a ring-shaped protein called the membrane attack complex (MAC), which digests holes in bacterial cell membranes and virus envelopes, leading to cell lysis. This step occurs after the cleavage of C5 to form C5a and C5b, which then initiates the assembly of C6, C7, C8, and multiple copies of C9 to form the MAC.

The Membrane Attack Stage of the Complement Cascade Involves