Augmentin combines amoxicillin with _____ to overcome enzymatic resistance to the antibiotic by the microbe.

Question

Quizplus · Accepted Answer

Clavulanic acid is a β-lactamase inhibitor that is combined with amoxicillin in Augmentin to prevent bacterial resistance. β-lactamase is an enzyme produced by bacteria that can inactivate β-lactam antibiotics such as penicillins and cephalosporins by breaking the β-lactam ring. Clavulanic acid inactivates β-lactamase enzymes and thus protects amoxicillin from being degraded by these enzymes, allowing it to be effective against a wider range of bacteria.

Augmentin Combines Amoxicillin with _____ to Overcome Enzymatic Resistance to the Antibiotic