Which of the following is most directly responsible for cell lysis in Type 2 hypersensitivity reactions?
A)IgG antibodies
B)IgM antibodies
C)complement activation
D)IgE antibodies
E)NK cells
F)TC cells

Question

Quizplus · Accepted Answer

Complement activation is directly responsible for cell lysis in Type 2 hypersensitivity reactions. This occurs when IgG or IgM antibodies bind to antigens on the surface of cells, activating the complement cascade which results in the formation of a membrane attack complex (MAC) that causes cell lysis.

Which of the Following Is Most Directly Responsible for Cell