Severe combined immunodeficiencies (SCIDs) are due to
A)autoantibodies.
B)delayed hypersensitivity.
C)congenital absence or immaturity of the thymus gland.
D)failure of B cell development and maturity.
E)a genetic defect in the development of both T-cells and B cells.

Question

Quizplus · Accepted Answer

Severe combined immunodeficiencies (SCIDs) are due to a genetic defect in the development of both T-cells and B cells. This defect can occur at various stages and can result in a lack of both T cells and B cells or a lack of function of these cells. Without functional immune cells, individuals with SCID are unable to mount an effective immune response and are highly susceptible to infections.

Severe Combined Immunodeficiencies (SCIDs) Are Due to