A serious limitation of using a retrovirus as a vector for gene therapy is that
A)the retrovirus may insert into a proto-oncogene,causing cancer.
B)a genetically modified retrovirus causes AIDS.
C)it causes ADA accumulation.
D)reverse transcriptase will not work in human cells.

Question

Quizplus · Accepted Answer

Retroviruses have the potential to insert their genetic material into the host genome, potentially disrupting normal gene function. If a retrovirus inserts itself into a proto-oncogene, it may activate it, leading to uncontrolled cell growth and potentially causing cancer. This risk limits the use of retroviruses as vectors for gene therapy.

A Serious Limitation of Using a Retrovirus as a Vector