Positional cloning
A)seeks regions of the genome shared by the members of large families who have the same Mendelian disorder.
B)scans and then sequences the human genome chromosome by chromosome,in size order.
C)determines the sequence of protein-encoding genes on a chromosome.
D)identifies expressed sequence tags in genes of interest.

Question

Quizplus · Accepted Answer

Positional cloning seeks to identify the specific gene or genomic region responsible for a particular disorder or trait. One way to do this is to study families with a known Mendelian disorder, identifying regions of the genome that are shared by all affected members, and then narrowing down to the specific gene(s) within those regions.

Positional Cloning