The maintenance of a resting potential in a neuron depends upon the functioning of the Na,K-ATPase pumps in the membrane.

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The Na,K-ATPase pumps play a critical role in maintaining the resting potential of a neuron by actively moving sodium ions out of the cell and potassium ions into the cell, against their concentration gradients. This helps to establish and maintain the negative charge inside the cell that is necessary for the proper functioning of the neuron. Without the Na,K-ATPase pumps, the resting potential would rapidly decay and the neuron would be unable to generate action potentials or transmit information effectively.

The Maintenance of a Resting Potential in a Neuron Depends