Mutations in complement proteins 1 through 4 directly affect the structure of the membrane attack complex.

Question

Quizplus · Accepted Answer

Complement proteins 1 through 4 are involved in the early stages of the complement activation pathways (classical, lectin, and alternative pathways) and do not directly affect the structure of the membrane attack complex (MAC), which is formed by the terminal complement components C5b, C6, C7, C8, and multiple C9 molecules.

Mutations in Complement Proteins 1 Through 4 Directly Affect the Structure