Two-year-old Zack has an inherited disorder in which his body cannot break down fat.He will probably die by the time he is 4.Which of the following diseases is Zack most likely suffering from?
A)Phenylketonuria
B)Sickle-cell anemia
C)Tay-Sachs disease
D)Down syndrome

Question

Quizplus · Accepted Answer

Zack is likely suffering from Tay-Sachs disease, which is an inherited disorder that prevents the breakdown of a fatty substance called ganglioside. This builds up in the brain and causes damage, leading to developmental and neurological problems. The condition usually begins around 3 to 6 months of age and progresses rapidly, with affected children typically dying by the age of 4. Phenylketonuria (A) is a metabolic disorder that affects the breakdown of the amino acid phenylalanine, which can lead to intellectual disability if untreated. Sickle-cell anemia (B) is a genetic disorder that causes misshapen, and malfunctioning red blood cells, leading to a variety of complications. Down syndrome (D) is a genetic disorder caused by the presence of an extra chromosome 21, leading to intellectual disability and other health problems. None of these conditions affect the breakdown of fats, so they are not the likely cause of Zack's condition.

Two-Year-Old Zack Has an Inherited Disorder in Which His Body