What is codon bias? If synonymous substitutions give the same amino acid,why should there be a bias in which codons encode that amino acid?

Name: What is codon bias? If synonymous substitutions give the same amino acid,why should there be a bias in which codons encode that amino acid?
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The Answer of What is codon bias? If synonymous substitutions give the same amino acid,why should there be a bias in which codons encode that amino acid?

What Is Codon Bias? If Synonymous Substitutions Give the Same