Blocking NMDA synapses has what effect, if any, on LTP?
A) There is no effect on LTP.
B) It enhances the establishment of LTP.
C) It prevents the establishment of LTP.
D) In prevents the maintenance of previously established LTP.

Question

Quizplus · Accepted Answer

Blocking NMDA synapses prevents the establishment of LTP. This is because NMDA receptors are required for the induction of LTP. Without them, calcium cannot enter the postsynaptic neuron to trigger the necessary changes in the strength of the synapse. Therefore, blocking NMDA synapses will prevent the establishment of LTP.

Blocking NMDA Synapses Has What Effect, If Any, on LTP