If a drug has high affinity and low efficacy, what effect does it have on the postsynaptic neuron?
A) antagonistic
B) agonistic
C) proactive
D) destructive

Question

Quizplus · Accepted Answer

A drug with high affinity and low efficacy will bind strongly to the receptor but will not activate it fully, resulting in a decrease in the activity of the postsynaptic neuron. This is characteristic of an antagonistic effect, as it opposes the action of neurotransmitters that would normally activate the receptor.

If a Drug Has High Affinity and Low Efficacy, What