What would be a primary advantage of using an attenuated agent rather than just an antigen from that agent for a vaccine?
A)This is actually a disadvantage-it's much more dangerous to use an attenuated agent over a subunit (single antigen)vaccine due to the possibility of reversion of the microbe to a pathogenic state.
B)An attenuated agent strongly stimulates ONLY the antibody production (humoral response)of the adaptive immune system.This provides the best and strongest long-term protection.
C)An attenuated agent strongly stimulates ONLY the cytotoxic T cell (CTL,cell-mediated)side of the adaptive immune system.This provides the best and strongest long-term protection.
D)An attenuated agent strongly stimulates both the humoral (antibody)AND cell-mediated (T cell)portions of the adaptive immune response,giving the best comprehensive long-term protection available.

Question

Quizplus · Accepted Answer

Using an attenuated agent as a vaccine provides comprehensive long-term protection by strongly stimulating both the humoral (antibody) and cell-mediated (T cell) portions of the adaptive immune response. This is because attenuated agents are weakened but still live microbes that can replicate and trigger a strong immune response. In contrast, subunit vaccines only contain a single antigen and may not provide as strong or long-lasting of an immune response. While there is a small risk of the attenuated agent reverting to a pathogenic state, this risk is outweighed by the benefits of the strong and comprehensive immune protection that an attenuated vaccine can provide.

What Would Be a Primary Advantage of Using an Attenuated