You engineer a chromosomally XY mouse in which the SRY gene is inactivated.What do you expect to observe in this mouse?
A)The mouse will develop male anatomic features.
B)The mouse will develop female anatomic features.
C)The mouse's Y chromosome will convert into an X chromosome.
D)The mouse's X chromosome will convert into a Y chromosome.
E)The mouse will exhibit an additional X chromosome (making it XXY).

Question

Quizplus · Accepted Answer

The SRY gene, found on the Y chromosome, is responsible for the initiation of male development. Inactivation of this gene would lead to the development of female anatomic features, even if the mouse has XY chromosomes.

You Engineer a Chromosomally XY Mouse in Which the SRY