The condition sickle cell anemia is due to
A)the insertion of an amino acid.
B)the deletion of an amino acid.
C)substitution of an amino acid.
D)failure to synthesize a hemoglobin molecule.
E)unequal recombination resulting in the deletion of the $\beta$-chain hemoglobin gene.

Question

Quizplus · Accepted Answer

Sickle cell anemia is caused by a single nucleotide substitution that changes the sixth amino acid in the beta-globin chain of hemoglobin from glutamic acid to valine. This change alters the shape of red blood cells, causing them to become rigid and sickle-shaped, resulting in various health problems.

The Condition Sickle Cell Anemia Is Due to A)the Insertion β\betaβ

The Condition Sickle Cell Anemia Is Due to
A)the Insertion $\beta$