Damage to the orbitofrontal cortex reduces people's inhibitions and self-concern.

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Damage to the orbitofrontal cortex has been known to result in impaired decision-making, increased risk-taking behavior, and decreased ability to regulate emotions and social behavior. This is believed to be due to the role the orbitofrontal cortex plays in inhibiting impulses and integrating information from different regions of the brain to guide decision-making. As a result, damage to this area can lead to reduced inhibitions and self-concern.

Damage to the Orbitofrontal Cortex Reduces People's Inhibitions and Self-Concern