Which statement is false about the pathophysiology of acute pancreatitis?
A) Pancreatic acinar cells metabolize ethanol,which generates toxic metabolites.
B) Injury to the pancreatic acinar cells permit leakage of pancreatic enzymes,which digest pancreatic tissue.
C) Acute pancreatitis is an autoimmune disease in which immunoglobulins G (IgG)coats the pancreatic acinar cells so they are destroyed by the pancreatic enzymes.
D) When gallstones are present,bile flows into the pancreas contributing to attacks.

Question

Quizplus · Accepted Answer

Acute pancreatitis is not an autoimmune disease. It is primarily caused by the leakage of pancreatic enzymes due to injury to the pancreatic acinar cells, which can be triggered by a variety of factors such as alcohol ingestion, gallstones, and infections. This inappropriate activation of digestive enzymes results in autodigestion of the pancreatic tissue and subsequent inflammation. B and D are accurate statements about the pathophysiology of acute pancreatitis. A is partially accurate - while ethanol metabolism can generate toxic metabolites, this is not the only cause of pancreatitis associated with alcohol consumption.

Which Statement Is False About the Pathophysiology of Acute Pancreatitis