What is the primary mechanism of atherogenesis?
A) The release of the inflammatory cytokines tumor necrosis factor alpha (TNF-),interferon gamma (IFN-),and interleukin 1 (Il-1)
B) The release of the growth factor granulocyte-macrophage colony-stimulating factor (GM-CSF)
C) The release of toxic oxygen radicals that oxidize low-density lipoproteins (LDL)
D) The release of the inflammatory cytokines interferon beta (IFN-ß),interleukin 6 (Il-6),and granulocyte colony-stimulating factor (G-CSF)

Question

Quizplus · Accepted Answer

The primary mechanism of atherogenesis is the release of toxic oxygen radicals that oxidize low-density lipoproteins (LDL), which initiates an inflammatory response and the formation of atherosclerotic plaques. The other cytokines and growth factors listed may also play a role in the development and progression of atherosclerosis, but they are not the primary mechanism.

What Is the Primary Mechanism of Atherogenesis