In hemolytic anemia,when does jaundice occur?
A) Only when erythrocytes are destroyed in the spleen
B) Only when heme destruction exceeds the liver's ability to conjugate and excrete bilirubin
C) Only when the patient has elevations in aspartate transaminase (AST)and alanine transaminase (ALT)
D) Only when the erythrocytes are coated with an immunoglobulin

Question

Quizplus · Accepted Answer

Jaundice occurs in hemolytic anemia when heme destruction exceeds the liver's ability to conjugate and excrete bilirubin. This occurs due to the breakdown of red blood cells and subsequent release of bilirubin into the bloodstream, which can accumulate and cause yellowing of the skin and eyes. Jaundice does not necessarily require erythrocyte destruction in the spleen or elevations in AST and ALT levels, nor does it depend on the presence of immunoglobulins on erythrocyte surfaces.

In Hemolytic Anemia,when Does Jaundice Occur