The difference between antibody allotypes and isotypes is:
A) isotypes are the differences in constant regions; allotypes are differences within isotypes
B) allotypes are the differences in constant regions; isotypes are differences within allotypes
C) isotypes are the difference in constant regions; allotypes are alternations in the hypervariable regions
D) isotypes are alternations in the hypervariable regions; allotypes are differences within isotypes
E) isotypes are alternations in the hypervariable regions of one person; allotypes are alternations in the hypervariable regions among a species

Question

Quizplus · Accepted Answer

Isotypes refer to the different forms of a particular class or subclass of antibody, which are based on differences in the constant regions. Allotypes, on the other hand, are individual variations within isotypes, which are determined by specific genetic polymorphisms that result in amino acid substitutions within the constant region of the antibody. Therefore, choice A is the correct answer since it accurately describes the difference between the two terms.

The Difference Between Antibody Allotypes and Isotypes Is