Why is the proteome larger than the genome?
A)Proteins may be modified by covalent addition of a variety of molecules
B)Not all genes are expressed in all cells at the same time
C)Each gene will produce multiple mRNAs which will produce multiple proteins so the ratio of the number of protein molecules the number of genes is greater than 1.
D)The total amount of protein in a cell as measured by mass is always greater than the total amount of DNA.

Question

Quizplus · Accepted Answer

The proteome is larger than the genome because proteins can undergo post-translational modifications, such as phosphorylation, glycosylation, and ubiquitination, which increase the diversity of proteins beyond the number of genes.

Why Is the Proteome Larger Than the Genome