Select the reasons that DNA synthesis occurs with a high degree of fidelity.
A) The hydrogen bonding between G and C or A and T is much more stable than between mismatched pairs.
B) The active site of DNA polymerase preferentially catalyzes the attachment of nucleotides when the correct bases are located in opposite strands.
C) DNA polymerase enzymatically removes mismatched nucleotides.
D) DNA polymerase has the ability to change the structure of the base in order to form the correct bond.

Question

Quizplus · Accepted Answer

The high fidelity of DNA synthesis is due to stable hydrogen bonding between correct base pairs (A), the preferential catalysis by DNA polymerase for correct base pairing (B), and the proofreading ability of DNA polymerase to remove mismatched nucleotides (C).

Select the Reasons That DNA Synthesis Occurs with a High