The experiment by Noll,1974,supported the observation that histones were regularly spaced on chromosomes because
A) digestion with increased amounts of DNase I resulted in one or a few bands.
B) limited digestion with DNase I resulted in DNA fragments that differed in size by approximately 200 bp.
C) digestion with low or high amounts of DNase I resulted in a fragment that was found at the bottom of the gel.
D) a digestion performed with a moderate amount of DNase I gave results that were very similar to results obtained with higher amounts of DNase I.

Question

Quizplus · Accepted Answer

The observation that DNA fragments differed in size by approximately 200 bp after limited digestion with DNase I supports the hypothesis that histones are regularly spaced on chromosomes, as the nucleosome structure consists of DNA wrapped around histone proteins in approximately 200 bp segments.

The Experiment by Noll,1974,supported the Observation That Histones Were Regularly