The match between HLAs determines the suitability of transplants,which HLA is known to generate the strongest transplant rejection reaction
A)HLA-A and HLA-B
B)HLA B27
C)HLA Dw3
D)HLA-DR

Question

Quizplus · Accepted Answer

HLA-DR is known to generate the strongest transplant rejection reaction because it is expressed on the surface of antigen-presenting cells and plays a major role in activating T cells, leading to rejection of the transplant. HLA-A and HLA-B are also important for determining transplant compatibility but do not generate the strongest rejection reaction. HLA B27 and HLA Dw3 are specific HLA types and do not provide a comprehensive answer to the question.

The Match Between HLAs Determines the Suitability of Transplants,which HLA