A 42 year old type I diabetic was experiencing increasing azotemia,as judged by his BUN and creatinine.His physician recommended he consult a nephrologist.A renal biopsy was recommended,and eventually performed,a representative section of which is shown in the accompanying photomicrograph.Which one of the following is the best diagnosis?
A)Acute proliferative glomerulonephritis
B)Diabetic glomerulosclerosis
C)Focal segmental glomerulonephritis
D)Membranous nephropathy
E)Mesangiocapillary (Membranoproliferative)glomerulonephritis
F)Minimal change disease
G)Normal glomerulus
H)Rapidly progressive glomerulonephritis (RPG

Question

A 42 year old type I diabetic was experiencing increasing azotemia,as judged by his BUN and creatinine.His physician recommended he consult a nephrologist.A renal biopsy was recommended,and eventually performed,a representative section of which is shown in the accompanying photomicrograph.Which one of the following is the best diagnosis? 
A)Acute proliferative glomerulonephritis 
B)Diabetic glomerulosclerosis 
C)Focal segmental glomerulonephritis 
D)Membranous nephropathy 
E)Mesangiocapillary (Membranoproliferative)glomerulonephritis 
F)Minimal change disease 
G)Normal glomerulus 
H)Rapidly progressive glomerulonephritis (RPG

Quizplus · Accepted Answer

Diabetes often gives rise to renal problems,the most common of which is glomerulosclerosis.Nodular areas of hyaline are seen (K).This pattern is referred to as Kimmelstiel-Wilson disease,or nodular diabetic glomerulosclerosis.

A 42 Year Old Type I Diabetic Was Experiencing Increasing