Which information regarding fatty streaks does the pathophysiology student learn? (Select all that apply.)
A)Fatty streaks progressively damage vessel walls.
B)Fatty streaks are capable of producing toxic oxygen radials.
C)When present, inflammatory changes occur to the vessel walls.
D)Oxidized low-density lipoproteins (LDLs) are involved in their formation.
E)Fatty streaks are formed by killer T cells filled with oxidized LDLs.

Question

Quizplus · Accepted Answer

The oxidized LDLs penetrate the intima of the arterial wall and are engulfed by macrophages. Macrophages filled with oxidized LDLs are called foam. Once these lipid-laden foam cells accumulate in significant amounts, they form a lesion called a fatty streak. Once formed, fatty streaks produce more toxic oxygen radicals and cause immunologic and inflammatory changes, resulting in progressive damage to the vessel wall. They are not formed by killer T cells.

Which Information Regarding Fatty Streaks Does the Pathophysiology Student Learn