When mismatched blood is administered causing an ABO incompatibility, how are the erythrocytes destroyed?
A)Complement-mediated cell lysis
B)Phagocytosis by macrophages
C)Phagocytosis in the spleen
D)Natural killer cells

Question

Quizplus · Accepted Answer

Erythrocytes are destroyed by complement-mediated lysis in individuals with autoimmune hemolytic anemia or as a result of an alloimmune reaction to ABO-mismatched transfused blood cells. Erythrocytes are not destroyed by phagocytosis or natural killer cells.

When Mismatched Blood Is Administered Causing an ABO Incompatibility, How