The maintenance of a resting potential in a neuron depends indirectly upon the functioning of the Na⁺,K⁺-ATPase pumps in the membrane.

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The Na⁺,K⁺-ATPase pumps play a crucial role in maintaining the resting potential of a neuron by actively pumping out three Na⁺ ions for every two K⁺ ions pumped in, which balances the passive diffusion of these ions across the membrane and contributes to the negative charge inside the cell. Without functioning pumps, the resting potential would quickly break down and the neuron would not be able to generate or transmit electrical signals effectively.

The Maintenance of a Resting Potential in a Neuron Depends