Which of the following statements is TRUE?
A)Phosphorylation by protein kinases can stimulate or inhibit the activity of effector proteins.
B)Ca²⁺ is not a second messenger.
C)Phosphodiesterase converts GMP into cGMP
D)Conversion of ATP to cAMP is a phosphorylation reaction.
E)Phospholipase C converts ATP to cAMP.

Question

Quizplus · Accepted Answer

Phosphorylation by protein kinases can either activate or deactivate the activity of effector proteins depending on the specific target and context. Ca²⁺ is a widely recognized second messenger. Phosphodiesterase converts cAMP into AMP, not GMP. Conversion of ATP to cAMP is not a phosphorylation reaction; rather, it involves the removal of two phosphate groups from ATP. Phospholipase C converts phosphatidylinositol 4,5-bisphosphate (PIP2) into inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), not ATP into cAMP.

Which of the Following Statements Is TRUE