What would most likely happen if there were a decrease in the number of acetylcholine receptors in an NMJ?
A) decreased neurotransmitter release into the synaptic cleft
B) increased sodium ion influx at the motor endplate
C) decreased action potential generation at the motor endplate
D) increased action potential generation at the motor endplate

Question

Quizplus · Accepted Answer

Acetylcholine receptors at the neuromuscular junction (NMJ) are crucial for the initiation of action potentials in muscle cells following the binding of acetylcholine released from motor neurons. A decrease in the number of these receptors would lead to a reduced ability to generate action potentials at the motor endplate, as there would be fewer sites for acetylcholine to bind and initiate the depolarization necessary for action potential generation.

What Would Most Likely Happen If There Were a Decrease