Osteomalacia is a disease in which inadequate calcification of the bone matrix results in bones becoming "soft" or rubbery to the point that they become very fragile and fracture easily.Hypersecretion of which of the following hormones would produce similar changes in bone?
A)calcitonin
B)calcitriol
C)PTH
D)growth Hormone
E)epinephrine

Question

Quizplus · Accepted Answer

The hormone that can produce similar changes in bone as osteomalacia is PTH (parathyroid hormone). PTH stimulates osteoclast activity, leading to an increase in bone resorption, which can result in decreased bone density and fragility. Osteomalacia is caused by a deficiency in calcitriol (a form of vitamin D), which reduces the absorption of calcium from the intestines and leads to inadequate mineralization of the bone matrix. Calcitonin helps regulate calcium homeostasis by inhibiting osteoclast activity, so hypersecretion of calcitonin would not result in soft bones. Growth hormone and epinephrine do not have direct effects on bone resorption or mineralization.

Osteomalacia Is a Disease in Which Inadequate Calcification of the Bone