A specific treponemal serologic test performed by overlaying whole treponemes that are fixed to a slide with serum from patients suspected of having syphilis and using fluorescein-conjugated antihuman antibody reagent to detect specific antitreponemal antibodies is called the _________ test.
A)RPR
B)FTA-ABS
C)VDRL
D)TP-PA

Question

Quizplus · Accepted Answer

Specific treponemal serologic tests include the FTA-ABS and the TP-PA tests.The FTA-ABS test is performed by overlaying whole treponemes that are fixed to a slide with serum from patients suspected of having syphilis because of a previous positive VDRL or RPR test.The patient's serum is first absorbed with non-T.pallidum treponemal antigens (sorbent)to reduce nonspecific cross-reactivity.Fluorescein-conjugated antihuman antibody reagent is then applied as a marker for specific antitreponemal antibodies in the patient's serum.

A Specific Treponemal Serologic Test Performed by Overlaying Whole Treponemes