A patient has been admitted with anaphylactic shock due to an unknown allergen.The nurse understands that the patient is probably having an immunoglobulin E (IgE)-mediated response as a result of what physiologic mechanism?
A) Direct activation of mast cells and basophils
B) Nonimmunologic stimulation of biochemical mediators
C) Repeat exposure to an antigen in the presence of preformed IgE antibodies
D) Activation of the systemic inflammatory response

Question

Quizplus · Accepted Answer

Immunoglobulin E (IgE)is an antibody that is formed as part of the immune response.The first time an antigen enters the body,an antibody IgE,specific for the antigen,is formed.The antigen-specific IgE antibody is then stored by attachment to mast cells and basophils.This initial contact with the antigen is known as a primary immune response.The next time the antigen enters the body,the preformed IgE antibody reacts with it,and a secondary immune response occurs.

A Patient Has Been Admitted with Anaphylactic Shock Due to an Unknown